Genes
Understandings:
A gene is a heritable factor that consists of a length of DNA and influences a specific characteristic.
A gene occupies a specific position on a chromosome.
A gene is a heritable factor that consists of a length of DNA and influences a specific characteristic.
A gene occupies a specific position on a chromosome.
Application: Comparison of the number of genes in humans with other species.
The number of genes in a species should not be referred to as genome size as this term is used for the total amount of DNA. At least one plant and one bacterium should be included in the comparison and at least
one species with more genes and one with fewer genes than a human.
The number of genes in a species should not be referred to as genome size as this term is used for the total amount of DNA. At least one plant and one bacterium should be included in the comparison and at least
one species with more genes and one with fewer genes than a human.
The birth and death of genes
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The genome is the whole of the genetic information of an organism.
The entire base sequence of human genes was sequenced in the Human Genome Project.
The entire base sequence of human genes was sequenced in the Human Genome Project.
International-mindedness:
Sequencing of the human genome shows that all humans share the vast majority of their base sequences but also that there are many single nucleotide polymorphisms that contribute to human diversity.
Sequencing of the human genome shows that all humans share the vast majority of their base sequences but also that there are many single nucleotide polymorphisms that contribute to human diversity.
Want to find where a particular sequence of DNA can be found? Use this search engine:
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Skill: Use of a database to determine differences in the base sequence of a gene in two species.
Aim 7: The use of a database to compare DNA base sequences.
The Genbank® database can be used to search for DNA base sequences. The cytochrome C gene sequence is available for many different organisms and is of particular interest because of its use in reclassifying organisms into three domains.
Skill: Use of a database to determine differences in the base sequence of a gene in two species.
Aim 7: The use of a database to compare DNA base sequences.
The Genbank® database can be used to search for DNA base sequences. The cytochrome C gene sequence is available for many different organisms and is of particular interest because of its use in reclassifying organisms into three domains.
Application: The causes of sickle cell anemia, including a base substitution mutation, a change to the base sequence of mRNA transcribed from it and a change to the sequence of a polypeptide in hemoglobin. Be able to recall the one specific base substitution that causes glutamic acid to be substituted by valine as the sixth amino acid in the hemoglobin polypeptide.
Theory of knowledge:
There is a link between sickle cell anemia and prevalence of malaria. How can we know whether there is a causal link in such cases or simply a correlation?
There is a link between sickle cell anemia and prevalence of malaria. How can we know whether there is a causal link in such cases or simply a correlation?
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Wach the video to the left from HHMi and answer the questions given in class. Video is 8:30 minutes
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