Inheritance
Theory of knowledge:
Mendel’s theories were not accepted by the scientific community for a long time. What factors would encourage the acceptance of new ideas by the scientific community?
Mendel’s theories were not accepted by the scientific community for a long time. What factors would encourage the acceptance of new ideas by the scientific community?
Understandings:
• Gametes are haploid so contain only one allele of each gene.
• The two alleles of each gene separate into different haploid daughter nuclei during meiosis.
• Fusion of gametes results in diploid zygotes with two alleles of each gene that may be the same allele or different alleles.
• Dominant alleles mask the effects of recessive alleles but co-dominant alleles have joint effects.
• Gametes are haploid so contain only one allele of each gene.
• The two alleles of each gene separate into different haploid daughter nuclei during meiosis.
• Fusion of gametes results in diploid zygotes with two alleles of each gene that may be the same allele or different alleles.
• Dominant alleles mask the effects of recessive alleles but co-dominant alleles have joint effects.
Skill: Construction of Punnett grids for predicting the outcomes of monohybrid genetic crosses.
Do the quiz at the right! Can you answer all correctly? Make sure to read the tutorials if needed.
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Skill: Comparison of predicted and actual outcomes of genetic crosses using real data.
Some genetic diseases are sex-linked. The pattern of inheritance is different with sex-linked genes due to their location on sex chromosomes.
Application: Red-green color blindness and hemophilia as examples of sex-linked inheritance.
Application: Red-green color blindness and hemophilia as examples of sex-linked inheritance.
Many genetic diseases in humans are due to recessive alleles of autosomal genes, although some genetic diseases are due to dominant or co-dominant alleles.
Many genetic diseases have been identified in humans but most are very rare.
Aim 8: Social implications of diagnosis of mutations, including the effects on the family and stigmatization.
Many genetic diseases have been identified in humans but most are very rare.
Aim 8: Social implications of diagnosis of mutations, including the effects on the family and stigmatization.
Application: Inheritance of cystic fibrosis and Huntington’s disease.
Click below to learn how the mutation works to form cystic fibrosis.
Research the different case studies to see how it is treated.
Click below to learn how the mutation works to form cystic fibrosis.
Research the different case studies to see how it is treated.
Application: Inheritance of ABO blood groups.
The expected notation for ABO blood group alleles is:
Phenotype Genotype
A IAIA or IAi
B IBIB or IBi
AB IAIB
O ii
The expected notation for ABO blood group alleles is:
Phenotype Genotype
A IAIA or IAi
B IBIB or IBi
AB IAIB
O ii
Radiation and mutagenic chemicals increase the mutation rate and can cause genetic diseases and cancer.
Application: Consequences of radiation after nuclear bombing of Hiroshima and accident at Chernobyl.
The year 2016 marks 70 years after Hiroshima was bombed August 6, 1945. There are multiple articles out about the victims and survivors. Chernobyl happened April 26, 1986.
Application: Consequences of radiation after nuclear bombing of Hiroshima and accident at Chernobyl.
The year 2016 marks 70 years after Hiroshima was bombed August 6, 1945. There are multiple articles out about the victims and survivors. Chernobyl happened April 26, 1986.