In depth Cellular respiration
Understandings:
• Cell respiration involves the oxidation and reduction of electron carriers. LEO says GER !
• Phosphorylation of molecules makes them less stable.
1) In glycolysis, glucose is converted to pyruvate in the cytoplasm.
liberating carbon dioxide.
The structure of the mitochondrion is adapted to the function it performs.
Applications and skills:
• Application: Electron tomography used to produce images of active mitochondria. Research micrographs of mitochondria!
• Skill: Analysis of diagrams of the pathways of aerobic respiration to deduce where decarboxylation and oxidation reactions occur.
• Skill: Annotation of a diagram of a mitochondrion to indicate the adaptations to its function.
Guidance:
• The names of the intermediate compounds in gylcolysis and the Krebs cycle are not required.
• Cell respiration involves the oxidation and reduction of electron carriers. LEO says GER !
• Phosphorylation of molecules makes them less stable.
1) In glycolysis, glucose is converted to pyruvate in the cytoplasm.
- Glycolysis gives a small net gain of 2 ATP without the use of oxygen.
- In aerobic cell respiration pyruvate is decarboxylated and oxidized, and converted into acetyl compound and attached to coenzyme A to form acetyl coenzyme A in the link reaction.
liberating carbon dioxide.
- Energy released by oxidation reactions is carried to the cristae of the mitochondria by reduced NAD and FAD.(NADH, FADH2)
- In chemiosmosis protons diffuse through ATP synthase to generate 34 ATP.
- Oxygen is needed to bind with the free protons to maintain the hydrogen gradient, resulting in the formation of water.
The structure of the mitochondrion is adapted to the function it performs.
Applications and skills:
• Application: Electron tomography used to produce images of active mitochondria. Research micrographs of mitochondria!
• Skill: Analysis of diagrams of the pathways of aerobic respiration to deduce where decarboxylation and oxidation reactions occur.
• Skill: Annotation of a diagram of a mitochondrion to indicate the adaptations to its function.
Guidance:
• The names of the intermediate compounds in gylcolysis and the Krebs cycle are not required.
Theory of knowledge:
Peter Mitchell’s chemiosmotic theory encountered years of opposition before it was finally accepted. For what reasons does falsification not always result in an immediate acceptance of new theories or a paradigm shift?
Peter Mitchell’s chemiosmotic theory encountered years of opposition before it was finally accepted. For what reasons does falsification not always result in an immediate acceptance of new theories or a paradigm shift?
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